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This test detects the VE mutation in the BRAF gene from formalin-fixed paraffin-embedded tumor tissue. BRAF VE mutation has been shown to be present. BRAF mutations are found to be recurrent in many cancer types. Of these, the mutation of valine to glutamic acid (VE) is the most prevalent. For BRAF Mutations. Tests Available: • BRAF VE by real-time PCR. • BRAF VE mutation only by Sanger sequencing. • BRAF full gene sequence analysis by.

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About BRAF VE. NSCLC is a common type of lung cancer. When it is metastatic (mNSCLC), the cancer cells have spread beyond the lungs to other parts of the. BRAF. Diagnostic testing of this gene is recommended to identify a potential genetic basis for a condition. This type of testing can inform prognosis and. BRAF Mutation Testing (malignant melanoma, colorectal cancer) About 50% of melanomas harbor activating mutations in BRAF. Over 90% of BRAF mutations.

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The BRAF gene is present in all of the cells in our body and it holds the instructions for making a protein by the same name, BRAF. Accurately detect BRAF V mutations in FFPET human melanoma tissue when selecting patients for treatment with vemurafenib. Although uncommon, BRAF mutations represent a valid potential target as multiple RAF kinase inhibitors are available. BRAF VE mutation is reported in 2% of.